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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95c4e7ce46fd5c7466e1c2b1847687394ed8bc7797cd11335ae548344022f07' 
  AND token = 'eMicMuFjy0bHQpOUCHoNLQNL4kQZB/wXf8e5R3VS0SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}