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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50340f4a2f789d1d6555edb9e2f8f1bbe6c94d8fe9101f4ae4d187e9d52f019f' 
  AND token = '9LoG4OENPAZyGXo9XNF+eGpl0DxxTVNdK/Q/SwmJY/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}