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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f2e2b564f1d3336e6e1832fa8d1edc15f6edd57eccbe42e634a86bcc279e4a' 
  AND token = 'XD6XrML7kSbvyJjbZRaaJwxp8lQrwjAof979BrSwJ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}