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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0e9a9f229af773cd6a60cddd35e36efa7091158147f0145c0851db75f764c2' 
  AND token = 'JagAWdRfzz8FtIBa3xa/AM/FKvRmodJh7RS3kttunAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}