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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de6ceefce0737f47b3acdd40ac250ca5bd24d0fd100ef8f52ef5633b3061666' 
  AND token = '77IT/o6EaFVq64mwA9f6HIeaRHPrsYCVhzcnJKuU+0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}