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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b9ac01466944a6eab804c2b37e41bdfd1b32af441ad727a62e8e03dd01f8f1' 
  AND token = 'th2tkET5NoshoO0aR+kRsoWAaPEGkp37bM8+wGRWcB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}