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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4462661737e6e2d36e6cab32b76c7ce12959e0b54ecc6827d58c86e0df3381e9' 
  AND token = 'HuguW9/KG14bNq0eEvUycFeFigLkixy0f6CTSuiBPqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}