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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d0d4c9cdd1d1b71e3db949e9f8c2946aa24617336453c323947f0e159906a3' 
  AND token = 'VfReAsf9Ua9LIfALBLKva7G5dxkkuIMuGwvibs0Dc94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}