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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c6f534a19d7d6cce93f8f6506bb935ccdf76e1b1a17574314d64ad518c0e0b' 
  AND token = 'GwcQHoMxmpf1pN7jX3Y2KXQM35aMHjy1DdfMIm16vj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}