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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cce8db0804b162d01027867c51050bb47fcab79b17bd122e836ffe8bf514116' 
  AND token = 'UtFHSuMwvtMJ1HqT71MW6nX2/8FdpXzRpkm0VFvVDW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}