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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '307198d16dae8693235c9a94b62a6ab3dfbf06c5bd7dfb788a3e0b2d83f4ae21' 
  AND token = 'kJEU77KFFntpxSM4qw7KDBdmafdTDGX01xxPIb6qVSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}