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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b39c37e6b49dd7790be9e77cdb0994509f361d978bbee6d175d48ec3a34d7b90' 
  AND token = 'H8PzJrX9evKzPFqQ76/l+hvAkKXQYL1mZ7Txmw2jZUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}