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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af9aa64518af946302fbbe27ca428874e8f0c04a70bf02d224fe5580d3cce6b' 
  AND token = 'e2sU1tLc5xn/NPzNk4H/oEEJoq3NjxR7j/YT1Nuq3U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}