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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2fc5da5ef0d81a12f68bccf1ae7066c8c4cad8ad022598b2e53cd4078f52005' 
  AND token = 'vxAR4AbtRuYhujw+P6u+vkTe+SlYeOzHGT7lVKDp4oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}