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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fb62f4696662328147954aad634e7233ecf8698be0de57a1332df0b81224573' 
  AND token = 'iVLS26ky67fCsimEkp0QIu57eofjWke0WpI87+zHUWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}