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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75eb51eafed2401fd0c4c0cbd577a1665a8a07fdab76e145c5d01a19ae9122e1' 
  AND token = 'okH9kw+4l1oAjT7BHDaCFOmIj0IDVxo3aiXUE1D1q/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}