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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2408718908253fae9a56177d7250f77a3f1ebcdf28e285a22192ff3585464c85' 
  AND token = 'ga/tzdb/NMHUSvyxNN0lW1OV7kapp6p30AZ2DKa4qwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}