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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce7bd19258d94b58929a9d557c51e6f75cc8997f419afe62806b5d702a4edbe4' 
  AND token = '88iuZuFWYuSQt5uLWZCCPlOdIT4mv8yDpo4Uf1ms8UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}