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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7141424929bb225a54a0ef5c4670d6d99febd160c5f7a2c54ab092a3a5259bc2' 
  AND token = 'eleaOQQGxMSNa5HeJ1e+EZj6eNVilKeSH0G0q8lDOuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}