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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018c7d2b58d15734876cbab629128a54573c2a608ab0512c3c6528cac6a13ab9' 
  AND token = '7kUCsl/XyMJFE8pkecUuc3hna7OPXYnJ0lEI6XtDEh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}