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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f320a3fa335aa07f58b4889b9f21a27122b1243e8b14b014b3d4a6e704d68b32' 
  AND token = 'a4pS5rBl7u5266tMwqlGiRHhZG7hqvo2zcBUP7mtyxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}