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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e8a14df5c8b24f332f38e9fbd22fe85de4aea2ac45278652fc1a624edd6a1a' 
  AND token = 'szw+Tco3ots+mPCSusKyaNjQuhhRPDyz+DVAxvUaGr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}