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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0bea6c7023d45f1f69e937496b636d0bb0a64de5ea2743f38c48d597c309b6' 
  AND token = '+gQ043iTmsjeBeYajduhKbsJZfOkQh4NL8eZWnsvLYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}