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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16377b8a82e08802731f789db160d7aae4f4d024ea26633b96a067eecb27a2c6' 
  AND token = 'zIKHbi+HEOfYvT00zik63IgTyo3pctwEDx0SYLttTYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}