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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb1afcf5286fa721063da4319614f21f41b36ac3a66eb9ff8bf1e8fa55eb4c1' 
  AND token = 'Y+gGS2MamM6rYmrWx4nHtdpgTHVpjHPG1S6UfWWg+zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}