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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a01e0c062bdafacc2f749e3f1658910786b9a8fd88432baa247cf0985924bf4' 
  AND token = 'Uk2ph9Hyfjn1ygSIGRzfUTUuZlx5Qo5/j0V8eNkFksI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}