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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e59927fbe6ade717ac948e9d01f783448aaea0b717f02986ed7b36b81d3045' 
  AND token = '2tsyDmmDor1hV4eNiUHg5+2zwEuqdaK0NHsshUiJ4TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}