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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bdd5441a3df3ddb2f63245152dcb79be9712e6766b020c360e8ad14b9bbb8d' 
  AND token = '4knCBC2SOD3jFwIaDe6n4FmYLkXjPMNXCCBEvgl2Afs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}