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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8779a8e00e3945aacf6697e7c588dec530d5b0dc1da2693acd31554002a95682' 
  AND token = 'oDdp/Gu8gvxhBv+MROiRKOTZtJKcTzkNAqeXfeiff/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}