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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f618a3d5ff52621bc5cb1f05fe119b3e08521f37fa06216b278f1151ac3889c' 
  AND token = 'z9AvD+iPGa0dmaiggrWgqZK+8TnJ1y7fz535/rB+sEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}