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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa6aea6c260c1bbc402fb2c35b2da5057dc37f4087d5d48ff44d1e087f8c61f' 
  AND token = 'yEgIn74r1KV2T9PT5+dw93nYN6Oh9+EDrcQqfiZhEek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}