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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303f38fe0131757ee0ee895b454cb1bde072ee04a1f8e12a9d6b3fa72a77fb62' 
  AND token = 'Toqj+krdm/lD+4C9MhIW/0z1NT5mEddBH5SwdyiCAn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}