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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c482217384e80332d6c32698d3d058a03349b19fcb2c8f303b555c7ecc56de9b' 
  AND token = 'QG/1SJyaGOLwbfMuagedom8um16awSWERC2o/fot/XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}