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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c453b1e0eadf48753fee9f09c1c29915a5fd47c3a0f5be410bd4b9ed922521a' 
  AND token = 'lun4Y3FbwNHVj8i1Bf0FBLh57YW4kIy8CztzOncUQ14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}