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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff0d6b20f9de7bf60e7785df413bd14e19e28519a23fdb8c884e9d055625c62' 
  AND token = 'ZdovKvIdrBIXEgVsX+2ni7cC1pzFuzIkrR22QkU98qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}