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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2e307f203272a99af6bdf5e56b1a9bce7f8b24aecb081e6395a827f941228e' 
  AND token = 'MGSwr2Em002bH8Noda4+gjvVwfOlR1is3biJzDevK08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}