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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7948ff41813a09b41d3e1f1ebb8dcf60a74157492ba162377214602c77548374' 
  AND token = 'KO1ZxlpK9qa5YRNMMZdUS4q/LMYGQTBiK+lyREO5cn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}