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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d57d6ee67a6f73d66fcea53fbc75255a4302c2389bf68f485fab5e139fcb7a' 
  AND token = 'mrZoV2CMeHn75zAU7vKrdZ9SJ6bAaoUekJ7aCK7TMjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}