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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcbe36454d6d116e2d610d800ecbf463edd2d2c502fa3dbbf46189740978956' 
  AND token = '5y8b0eFjCT4XA/RFUiuHcmAw1biDou7mJTeCA/CnO3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}