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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af732873cab074edff6a688f58a310bd722178645288f931812ef3544ea888b1' 
  AND token = 'JWMw7BUlIpiTgjcXf+vRXQh13uheHD1CM3U4xhPkgVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}