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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d131cdd33a6aa20e37622ad0b81813173e8c278c71f7e80cb7653babb75ca5c' 
  AND token = 'LkpafgxDcUczmvoFpv45qVt7IJtpF9RBJP4fSXgVlIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}