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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd43759c86d6685a25af07baf91c03fc4ddf58677cd4e28c16abdd6d981a677' 
  AND token = 'v3rO6i9VVHZmVQYHJm2OyEoVPxix3FN5MPjTWYAtQmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}