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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21406ac48b833dcbca9cae4802d9778e982d1326f9f13e4d2f676fdd285677b' 
  AND token = 'CNj78r7ckzV0+FmHSOUo8NBKB9Cf50jFcE+nEKMIluQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}