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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6864cb35829fa87a78d82a62fee69fd213abdf13879f1d14f7a84bf63555d1c' 
  AND token = '8N4N7fqiyW+wm9WX/RESoRRweQ/2fTuRRcug7qu+ES0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}