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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0345ea2594c45508437d0b98a131812c2d621286c9d869bd4334bb8a56ad17bb' 
  AND token = 'TQ/hOn/jcY7x37L0rtAXDQzB0oCB9NCWDis/4lTHd9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}