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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e9f7105e75ae75dd72f468ba4d08ff13e7bfead8ed3ddc3ba21f928e569208' 
  AND token = '+pSJ1YuNZqpr0DFeAd9BydMPDX5n/GaNI17yegY0NXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}