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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c3d5d97fb2e6c70e1327ffd7e8c31175704ba7a657b1337fee62c38e50d93f' 
  AND token = 'LRCHnMs342/HgQAHZ/06CQ6dtOnnE4LQXSiEAyPjZ9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}