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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf4aacea4fbaea902d980e920f7b246e56b5cc904e6fe3041e4b5aeb320f01b6' 
  AND token = 'kYY4Q6P6VpVZ3HlQaS7816Nr7aW3lWhYS7k7cAcPm28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}