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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cbb126f5e349c3021e6a00779af81fc9df8a907ab1ccc009ba9e0e1bc0f30a0' 
  AND token = 'GNzVmEpUWDFLJ3WeoCD8hUaMPB55TuAf6Fs8/NGqUHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}