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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a0492a222aa038c387f19bdabc26ff41dddfc363c8d9c31929466b39f22187' 
  AND token = 'r651D0MAcbIoCb9lZg1mgX/1/LfLCb6xa39K7jAa5eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}